| 名稱 | AI-Edigene® BTK p.C481S Reference Standard Pl |
| 型號(hào) | CBP10549 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | AI-Edigene® BTK p.C481S Reference Standard Plus |
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10549AI-Edigene® BTK p.C481S Reference Standard Pl
- 詳細(xì)內(nèi)容
CBP10549 | |
| Format | Genomic DNA |
| Description | BTK, Bruton tyrosine kinase, is a non-receptor tyrosine kinase involved in B-cell activation and development (PMID: 24658273). BTK is commonly overexpressed in various hematological malignancies (PMID: 24658273) and BTK mutations have been linked to BTK inhibitor drug resistance (PMID: 28235842). |
| Technical Data | |
| DNA Change | c.1442G>C |
| AA Change | p.C481S |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | NM_000061.3 |
| Cosmic ID | COSM6053938 |
| Chr position(GRCh37) | chrX:100611164 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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