| 名稱 | TP53 p.PSS126fs Reference Standard 標(biāo)準(zhǔn)品 |
| 型號 | CBP10459 |
| 報價 |  |
| 特點(diǎn) | TP53 p.PSS126fs Reference Standard |
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10459TP53 p.PSS126fs Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10459 | |
| Gene | TP53 |
| Description | TP53, cellular tumor antigen p53, is a tumor suppressor (PMID: 30562755) involved in cell cycle arrest and apoptosis, and is the most frequently mutated gene in cancer (PMID: 10065147, PMID: 22713868). TP53 germline mutations are common in Li-Fraumeni syndrome (PMID: 30239254) and somatic missense mutations are frequent in almost all cancer types cancers (PMID: 30224644) and are also implicated in chemoresistance (PMID: 9927204, PMID: 24065105, PMID: 27066457). |
| Technical Data | |
| DNA Change | c.376-17_384del |
| AA Change | p.PSS126fs |
| Mutation type | Splice_Site |
| Zygosity | Heterozygous |
| Allelic Frequency | 76.50% |
| Transcript | ENST00000269305.4 |
| Cosmic ID | N/A |
| Chr position(GRCh37) | chr17:7578571_7578546 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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